Guidelines:


Guidelines for MRI in Paediatric Brain Tumours



SUPRATENTORIAL TUMOURS

At Presentation

Sequences:

Cranial

Axial dual echo SE (spin echo) or FSE (fast spin echo)
Coronal T1 SE
Post contrast (i.v. gadolinium DTPA) T1 SE in at least two orthogonal planes.

Spinal

Post contrast whole spine sagittal T1 SE Axial T1 SE if equivocal
Guideline parameters:
Cranial:- Slice thickness <5 mm
FOV (field of view) 180-230 em
Matrix <256x256 (effective)
T1 SE
TR:<800 msec.
TE: <25 msec
T2 SE
TR:2,000-2,600 msec,
TE:20/90 msec
T2 FSE
TR:3,000-4,000 msec,
TE:20/90 msec

Spinal:- T1 SE TR: <600 msec
TE: <25 msec
Slice thickness <4 mm
Contrast medium: i.v. line to be placed prior to attending MR department where possible. I.V. Gadolinium DTPA 0.1 mmol/kg

Immediate Post Surgery - (Assessment of Residual Tumour)

Timing: Within 72 hr
Sequences:
Cranial:- Coronal Tl SE
Axial dual echo SE/FSE
Post-contrast T1 SE in at least two orthogonal planes
Spinal:- Not recommended, see text
Parameters and contrast medium:- as above

Late Follow-up MRI

Timing:- Protocol driven - dependent on tumour type
Sequences:-
Cranial:- Coronal TI SE
Axial dual echo SE/FSE
Post-contrast TI SE in at least two orthogonal planes
Spine:- Post-contrast whole spine sagittal TI SE (If histology indicates tumour type with potential to seed through the CSF).
Parameters, contrast medium:- As before

INFRATENTORIAL TUMOURS

Presentation

Sequences:-
Cranial:- Whole brain axial coronal TI SE
Whole brain T2 SE/FSE axial
Sagittal T2 through brainstem for brain stem glioma
Post-contrast T 1 SE in at least two orthogonal planes
Spinal:- Post-contrast whole spine sagittal T1 SE
Parameters:- As for supratentorial lesions
Slice thickness <5 mm
Contrast medium:- i.v. line to be placed prior to attending MR department, when possible. I.V. Gadolinium DTPA 0.1 mmol/Kg.

Immediately Post-surgery -Assessment of Residual Tumour

Timing:- Within 72 hr
Sequences:-
Cranial:- Whole brain coronal T1 SE
Axial T2 SE/FSE
Post contrast T 1 SE in two orthogonal planes
Spinal:- Not recommended, see text
Parameters, contrast medium:- As before

Late Follow-up MRI

Parameters: As before
Timing:- Protocol driven (dependent on tumour type)
Sequence:-
Cranial:- Whole brain coronal T1 SE
Whole brain axial T2 SE/FSE Post contrast
T1 SE in two orthogonal planes
Spinal:- Post contrast sagittal T1 SE
Contrast medium:- As before

 

Abbreviations

FSE - Fast Spin Echo
SE - Spin Echo
TE - Time to Echo
TR - Time to Repeat